We believe that ongoing research into disease states and treatments is a vital part of improving our patients’ well-being. Research enables new cures and better treatments. We are committed to participating in cutting-edge research, allowing our patients to have access to the latest treatment options and furthering scientific development.

We have included brief summaries on clinical research trials which are currently enrolling.  We have grouped these trials by diagnosis, ranging from macular degeneration and diabetic macular edema to uveitis and ocular melanoma.

For more information on any of the studies, please contact the research department anytime with your specific questions 720-420-3265

Study Summaries

We are currently enrolling patients for these clinical trials.

Dry AMD

OPH2003  A Phase 2b Randomized, Double-Masked, Controlled Trial to Assess the Safety and Efficacy of Intravitreous Administration of Zimura™ (Anti-C5 Aptamer) in Subjects with Geographic Atrophy Secondary to Dry Age-Related Macular Degeneration (Ophthotech)

In this study, patients will receive monthly intravitreal injections. This is a 18 month study at the Red Rocks Medical Center.

Uveitis

Gilead  A Phase 2, Randomized, Placebo-Controlled Trial Evaluating the Efficacy and Safety of Filgotinib in Subjects with Active Non-infectious Uveitis (Gilead)

In this study, patients will receive a oral dose of medication daily.  This is a 60 week study at the Red Rocks Medical Center.

Wet AMD Naïve

OPT302 A Dose Ranging study of intravitreal OPT-302 in combination with ranibizumab, compared to ranibizumab alone in patients with wet AMD (OPTHEA)

In this study, patients will receive monthly intravitreal injections for 6 months. This is a 6 month study at the Red Rocks Medical Center.

OPH2007 A Open Label Trial to Assess the Safety of Zimura Administered in combination with Lucentis in Treatment Naïve Subjects with wet AMD (Ophthotech)

In this study, patients will receive monthly intravitreal injections up to 6 months.  This is a six month study at the Red Rocks Medical Center.

Central Retinal Vein Occlusion (CRVO)

Sapphire A randomized, masked, controlled trial to study the safety and efficacy of suprachoroidal CLS‑TA in conjunction with intravitreal aflibercept in subjects with retinal vein occlusion (Sapphire)  In this study, patients will receive monthly suprachoroidal injections for 6 months. This is a 6 month study at the Red Rocks Medical Center.